Bioinformatics

Bioinformatics is an interdisciplinary field that develops methods and software tools for better understanding biological data. 🚀


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Bioinformatics

Introduction about the Bioinformatics and Fields related to bioinformatics.

Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data.
This part we will focus on below list of questions:
1. What is bioinformatics?
2. What are the origins of bioinformatics?
3. What are the most common bioinformatics programs?
4. What are the most common bioinformatics technologies?
5. How are data analyzed in bioinformatics?
6. Fields related to bioinformatics

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Programming

Brifely introduce some programming language and the IDE-like software.

R is a programming language and free software environment for statistical computing and graphics that is supported by the R Foundation for Statistical Computing. The R language is widely used among statisticians and data miners for developing statistical software and data analysis.
R is a GNU package. The source code for the R software environment is written primarily in C, Fortran, and R. R is freely available under the GNU General Public License, and pre-compiled binary versions are provided for various operating systems.

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RStudio is an integrated development environment (IDE) for R. It includes a console, syntax-highlighting editor that supports direct code execution, as well as tools for plotting, history, debugging and workspace management.

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Tutorials

Bioinformatics is a computional biology, here we provide some tutorials for the common tools of bioinformatics

History of Computer

This part will briefly introduce the history of computer.

History of Internet

The Internet is a worldwide system of interconnected computer networks that use the TCP/IP set of network protocols to reach billions of users.

ClinVar Database

ClinVar aggregates information about genomic variation and its relationship to human health.

NIH Disaster Research Response (DR2)

The NIH Disaster Research Response Program (DR2) is the national framework for research on the medical and public health aspects of disasters and public health emergencies.

UCSC Genome Browser

UCSC Genome Browser is a web-based tool that provides a fast, easy way to display a specific region of a genome assembly, along with dozens of aligned annotation tracks.

Gene Expression Omnibus

GEO is a public functional genomics data repository supporting MIAME-compliant data submissions.

Database

Bioinformatics database is the starting point and operating platform for all bioinformatics work

Rfam

Rfam is a database containing information about non-coding RNA (ncRNA) families and other structured RNA elements. It is an annotated, open access database originally developed at the Wellcome Trust Sanger Institute in collaboration with Janelia Farm, and currently hosted at the European Bioinformatics Institute.
Rfam is designed to be similar to the Pfam database for annotating protein families.

MiRBase

In bioinformatics, miRBase is a biological database that acts as an archive of microRNA sequences and annotations. As of September 2010 it contained information about 15,172 microRNAs. This number has rose to 38589 by March 2018. The miRBase registry provides a centralised system for assigning new names to microRNA genes.

Software

Here we provide some popular tools for various kinds of fields.

DNA Modifications

Including: DNA modification analysis, DNA methylation array analysis, Enrichment Analysis,BS-seq analysis.

Nucleosome Positioning

Including: Nucleosome positioning, MNase-seq analysis, ATAC-seq analysis.

DNA-Protein Interactions

Including: HT-SELEX Analysis, DNase-seq Analysis, ChIO-seq Analysis.

Journals

The comprehensive list of the bioinformatics and computational biology journals and conferences (in alphabetical order).

Please Click other labels on the bar to see details.

This label is used for folding the details of the Journals part.

Contact

Please contact to Correcting error and/or Giving advices. Thanks!