Signal Transduction Pathway Databases
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
Database:
Pathway Interaction Database (PID)
The Pathway Interaction Database (PID) is a free biomedical database of human cellular signaling pathways. The database contains information about the molecular interactions and reactions that take place in cells, with a particular focus on processes that might be relevant to cancer research and treatment.
Reactome
Reactome is a free online database of biological pathways. There are several Reactomes that concentrate on specific organisms, the largest of these is focused on human biology, the following description concentrates on the human Reactome.
WikiPathways
WikiPathways is a community resource for contributing and maintaining content dedicated to biological pathways.
Metabolic Pathway Databases
In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell. The reactants, products, and intermediates of an enzymatic reaction are known as metabolites, which are modified by a sequence of chemical reactions catalyzed by enzymes.[1]:26 In most cases a metabolic pathway, the product of one enzyme acts as the substrate for the next. However, set products are considered waste and removed from the cell. These enzymes often require dietary minerals, vitamins, and other cofactors to function.
Database:
BioCyc database collection
The BioCyc database collection is an assortment of organism specific Pathway/ Genome Databases (PGDBs). They provide reference to genome and metabolic pathway information for thousands of organisms. As of December 2016, there are 9300 databases within BioCyc.
BRENDA
BRENDA (The Comprehensive Enzyme Information System) is an information system representing one of the most comprehensive enzyme repositories.
KEGG
KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.